diff --git a/Penumbra/Mods/Manager/ModManager.cs b/Penumbra/Mods/Manager/ModManager.cs
index 32dac049..77385bbd 100644
--- a/Penumbra/Mods/Manager/ModManager.cs
+++ b/Penumbra/Mods/Manager/ModManager.cs
@@ -1,5 +1,6 @@
 using OtterGui.Services;
 using Penumbra.Communication;
+using Penumbra.Interop;
 using Penumbra.Mods.Editor;
 using Penumbra.Mods.Manager.OptionEditor;
 using Penumbra.Services;
@@ -303,6 +304,9 @@ public sealed class ModManager : ModStorage, IDisposable, IService
             if (!firstTime && _config.ModDirectory != BasePath.FullName)
                 TriggerModDirectoryChange(BasePath.FullName, Valid);
         }
+
+        if (CloudApi.IsCloudSynced(BasePath.FullName))
+            Penumbra.Log.Warning($"Mod base directory {BasePath.FullName} is cloud-synced. This may cause issues.");
     }
 
     private void TriggerModDirectoryChange(string newPath, bool valid)
diff --git a/Penumbra/Penumbra.cs b/Penumbra/Penumbra.cs
index b22d049d..f036adc7 100644
--- a/Penumbra/Penumbra.cs
+++ b/Penumbra/Penumbra.cs
@@ -23,6 +23,7 @@ using Dalamud.Plugin.Services;
 using Lumina.Excel.Sheets;
 using Penumbra.GameData;
 using Penumbra.GameData.Data;
+using Penumbra.Interop;
 using Penumbra.Interop.Hooks;
 using Penumbra.Interop.Hooks.PostProcessing;
 using Penumbra.Interop.Hooks.ResourceLoading;
@@ -211,10 +212,11 @@ public class Penumbra : IDalamudPlugin
 
     public string GatherSupportInformation()
     {
-        var sb         = new StringBuilder(10240);
-        var exists     = _config.ModDirectory.Length > 0 && Directory.Exists(_config.ModDirectory);
-        var hdrEnabler = _services.GetService<RenderTargetHdrEnabler>();
-        var drive      = exists ? new DriveInfo(new DirectoryInfo(_config.ModDirectory).Root.FullName) : null;
+        var sb          = new StringBuilder(10240);
+        var exists      = _config.ModDirectory.Length > 0 && Directory.Exists(_config.ModDirectory);
+        var cloudSynced = exists && CloudApi.IsCloudSynced(_config.ModDirectory);
+        var hdrEnabler  = _services.GetService<RenderTargetHdrEnabler>();
+        var drive       = exists ? new DriveInfo(new DirectoryInfo(_config.ModDirectory).Root.FullName) : null;
         sb.AppendLine("**Settings**");
         sb.Append($"> **`Plugin Version:              `** {_validityChecker.Version}\n");
         sb.Append($"> **`Commit Hash:                 `** {_validityChecker.CommitHash}\n");
@@ -223,7 +225,8 @@ public class Penumbra : IDalamudPlugin
         sb.Append($"> **`Operating System:            `** {(Dalamud.Utility.Util.IsWine() ? "Mac/Linux (Wine)" : "Windows")}\n");
         if (Dalamud.Utility.Util.IsWine())
             sb.Append($"> **`Locale Environment Variables:`** {CollectLocaleEnvironmentVariables()}\n");
-        sb.Append($"> **`Root Directory:              `** `{_config.ModDirectory}`, {(exists ? "Exists" : "Not Existing")}\n");
+        sb.Append(
+            $"> **`Root Directory:              `** `{_config.ModDirectory}`, {(exists ? "Exists" : "Not Existing")}{(cloudSynced ? ", Cloud-Synced" : "")}\n");
         sb.Append(
             $"> **`Free Drive Space:            `** {(drive != null ? Functions.HumanReadableSize(drive.AvailableFreeSpace) : "Unknown")}\n");
         sb.Append($"> **`Game Data Files:             `** {(_gameData.HasModifiedGameDataFiles ? "Modified" : "Pristine")}\n");
diff --git a/Penumbra/UI/Tabs/SettingsTab.cs b/Penumbra/UI/Tabs/SettingsTab.cs
index ded56bb1..308cc471 100644
--- a/Penumbra/UI/Tabs/SettingsTab.cs
+++ b/Penumbra/UI/Tabs/SettingsTab.cs
@@ -14,6 +14,7 @@ using OtterGui.Text;
 using OtterGui.Widgets;
 using Penumbra.Api;
 using Penumbra.Collections;
+using Penumbra.Interop;
 using Penumbra.Interop.Hooks.PostProcessing;
 using Penumbra.Interop.Services;
 using Penumbra.Mods.Manager;
@@ -59,6 +60,9 @@ public class SettingsTab : ITab, IUiService
 
     private readonly TagButtons _sharedTags = new();
 
+    private string _lastCloudSyncTestedPath = string.Empty;
+    private bool   _lastCloudSyncTestResult = false;
+
     public SettingsTab(IDalamudPluginInterface pluginInterface, Configuration config, FontReloader fontReloader, TutorialService tutorial,
         Penumbra penumbra, FileDialogService fileDialog, ModManager modManager, ModFileSystemSelector selector,
         CharacterUtility characterUtility, ResidentResourceManager residentResources, ModExportManager modExportManager, HttpApi httpApi,
@@ -208,6 +212,15 @@ public class SettingsTab : ITab, IUiService
         if (IsSubPathOf(gameDir, newName))
             return ("Path is not allowed to be inside your game folder.", false);
 
+        if (_lastCloudSyncTestedPath != newName)
+        {
+            _lastCloudSyncTestResult = CloudApi.IsCloudSynced(newName);
+            _lastCloudSyncTestedPath = newName;
+        }
+
+        if (_lastCloudSyncTestResult)
+            return ("Path is not allowed to be cloud-synced.", false);
+
         return selected
             ? ($"Press Enter or Click Here to Save (Current Directory: {old})", true)
             : ($"Click Here to Save (Current Directory: {old})", true);